The Journal of Industry and Technology

Industrial Analytical Instrumentation

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Microfluidics

Novel microfluidic droplet-in-droplet system
offers monodisperse double emulsions

Microfluidic products expert Dolomite offer their Double Emulsion System for creating micron sized emulsion droplets that contain still smaller droplets inside. It enables unrivalled reproducibility and selectivity of droplet size of both outer and inner phases with either oil-in-water-in-oil or water-in-oil-in-water droplets. The Double Emulsion System is highly beneficial to applications in the food industry, in pharmaceuticals and cosmetics that use double emulsions as delivery vehicles or encapsulation solutions for various active ingredients, or more generally in paints and coatings.

Dolomite's systems for producing double emulsions offer highly consistent and more monodisperse droplets than the traditional two step emulsification process that uses conventional rotor-stator or high pressure valve homogenizers.

The key elements of the Double Emulsion System are the Mitos P-Pump, which delivers precise flow to ensure droplet monodispersity, and the glass Double Emulsion Chip which has a hydrophobic capillary and hydrophilic flow focussing droplet junction, enabling the formation of droplets ranging from 80 to 120μm (outer) and 50 to 90μm (inner) in diameter.

Further advantages the system offers can be found in shielding sensitive biological structures from forces exerted by the sheath fluid, preservation of the linkage between an individual microorganism and the substances it secretes allowing for a screening of metabolites and the opportunity to perform in vitro analyses of biomolecules detached from the respective microorganisms.

To view the system, as well as read a supporting application note, view website: www.dolomite-microfluidics.com/webshop/double_emulsion_system

The Dolomite Centre Limited in profile
Established in 2005 as the world's first Microfluidic Application Centre, Dolomite focused on working with customers to turn their concepts for microfluidic applications into reality. Today, Dolomite is the world leader in solving microfluidic problems. With offices in the UK and US and distributors throughout the rest of the world, its clients range from universities developing leading-edge analytical equipment, to manufacturers of chemical, life sciences and clinical diagnostics systems.

Dolomite is pioneering the use of microfluidic devices for small-scale fluid control and analysis, enabling manufacturers to develop more compact, cost-effective and powerful instruments. By combining specialist glass, quartz and ceramic technologies with knowledge of high performance microfluidics, Dolomite is able to provide solutions for a broad range of application areas including environmental monitoring, clinical diagnostics, food and beverage, nuclear, agriculture, petrochemical, cosmetics, pharmaceuticals and chemicals. Furthermore Dolomite's in-house micro-fabrication facilities that include clean rooms and precision glass processing facilities allow to prototype and test all solutions rapidly which ensures a faster development cycle and reduces the time to market.

For further information, view website: www.dolomite-microfluidics.com 
Refer to page 824 

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